Biotechnology and Health Sciences Biotechnology and Health Sciences Biotech Health Sci http://www.Biotech-health.portal.tools 2383-0271 2383-028X 10.5812/bhs en jalali 2021 5 10 gregorian 2021 5 10 3 2
en 10.17795/bhs-35687 Characteristics of Seropositive Hepatitis B and C Thalassemia Major Patients in South-East of Iran Characteristics of Seropositive Hepatitis B and C Thalassemia Major Patients in South-East of Iran research-article research-article Conclusions

Results demonstrated the relatively high prevalence of HCV infection in the patients. Applying sensitive methods to screen blood units is recommended to minimize the risk of transfusion associated hepatitis.

Objectives

The current study aimed to evaluate characteristics of hepatitis in patients with β-TM visiting Imam Khomeini Hospital of Zabol, in Sistan and Baluchistan province of Iran.

Patients and Methods

There were 90 patients with β-TM. General demographic and laboratory results were obtained by interviews and reviewing clinical and laboratory histories. Data for anti-HCV, HBs antigen and anti-HBs were extracted from latest archived records, and analyzed using SPSS ver. 19.

Results

Males and females comprised 51% and 49% of the patients, respectively. Mean age of the patients was 14.8±7.4 years old. Anti-HCV and HBs antigen were detected in 10% and 3.3% of the patients, respectively. Significant difference was found between the mean age of anti-HCV positive (20.1 ± 3.6, 95% CI: 17.3 - 22.9) and negative (14.2 ± 7.5, 95% CI: 12.5 - 15.9) patients (P = 0.02). Mean ferritin value was measured 4702 ± 2743 ng/mL. A significant correlation was observed between serum ferritin level and age (r = 0.3, P = 0.01). Hepatic enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) had mean levels of 51.8 ± 32.8 IU/L and 58.8 ± 59 IU/L, respectively. No significant association was identified between hepatitis status and either ferritin or hepatic enzymes levels.

Background

Hepatitis is a serious blood born infection in patients with β-thalassemia major (β-TM). There was no previous report on hepatitis prevalence in patients with β-TM in Zabol, Iran.

Conclusions

Results demonstrated the relatively high prevalence of HCV infection in the patients. Applying sensitive methods to screen blood units is recommended to minimize the risk of transfusion associated hepatitis.

Objectives

The current study aimed to evaluate characteristics of hepatitis in patients with β-TM visiting Imam Khomeini Hospital of Zabol, in Sistan and Baluchistan province of Iran.

Patients and Methods

There were 90 patients with β-TM. General demographic and laboratory results were obtained by interviews and reviewing clinical and laboratory histories. Data for anti-HCV, HBs antigen and anti-HBs were extracted from latest archived records, and analyzed using SPSS ver. 19.

Results

Males and females comprised 51% and 49% of the patients, respectively. Mean age of the patients was 14.8±7.4 years old. Anti-HCV and HBs antigen were detected in 10% and 3.3% of the patients, respectively. Significant difference was found between the mean age of anti-HCV positive (20.1 ± 3.6, 95% CI: 17.3 - 22.9) and negative (14.2 ± 7.5, 95% CI: 12.5 - 15.9) patients (P = 0.02). Mean ferritin value was measured 4702 ± 2743 ng/mL. A significant correlation was observed between serum ferritin level and age (r = 0.3, P = 0.01). Hepatic enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) had mean levels of 51.8 ± 32.8 IU/L and 58.8 ± 59 IU/L, respectively. No significant association was identified between hepatitis status and either ferritin or hepatic enzymes levels.

Background

Hepatitis is a serious blood born infection in patients with β-thalassemia major (β-TM). There was no previous report on hepatitis prevalence in patients with β-TM in Zabol, Iran.

β-Thalassemia Major;Anti-HCV, HBs Antigen;Anti-HBs;Ferritin β-Thalassemia Major;Anti-HCV, HBs Antigen;Anti-HBs;Ferritin http://www.Biotech-health.portal.tools/index.php?page=article&article_id=35687 Ali Bazi Ali Bazi Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran; Zabol University of Medical Sciences, Zabol, IR Iran. Tel/Fax: +98-5432232166 Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran; Zabol University of Medical Sciences, Zabol, IR Iran. Tel/Fax: +98-5432232166 Ebrahim Mirimoghaddam Ebrahim Mirimoghaddam Department of Genetics, Genetics of Non-Communicable Disease Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran Department of Genetics, Genetics of Non-Communicable Disease Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran Daryoush Rostami Daryoush Rostami Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran Mansour Dabirzadeh Mansour Dabirzadeh Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, IR Iran
en 10.17795/bhs-34453 Expression Analysis of ARMC3, a Testis-Specific Gene, in Breast Cancer Patients Expression Analysis of <italic>ARMC3</italic>, a Testis-Specific Gene, in Breast Cancer Patients research-article research-article Conclusions

Expression of ARMC3 in tumor samples and normal adjacent tissue is very important. The expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. Accordingly, aberrant expression of ARMC3 in tumor samples may be an attractive candidate for use as a tumor marker.

Results

Overall, 43.6% of tumors and 25.6% of normal adjacent tissues expressed ARMC3. ARMC3 was overexpressed in 41% of tumor samples (P = 0.00) and showed decreased expression in 46.2% (P = 0.00). Also, the expression of this gene in 12.8% of tumors was unchanged, which was statistically significant. It should be noted that all samples expressed ACTB gene.

Materials and Methods

Eighty samples including 40 tumor samples and 40 normal adjacent tissue samples, were gathered from the ICBC biobank. RNA extraction was carried out on all samples. The extracted RNA was treated by DNaseI, after which cDNA was synthesized. Expression of ARMC3 with ACTB (internal control) was studied using Real-Time PCR (polymerase chain reaction).

Background

Breast cancer is the most prevalent cancer among women. Biomarkers that are expressed in tumors play a pivotal role in diagnosis and treatment. Cancer-testis (CT) antigens are predominantly expressed in the testis and also have inappropriate expression in various tumor types. In the case of expression in tumors, they will be used as immunotherapy targets.

Objectives

Expression of ARMC3, a CT antigen, was analyzed to determine its potential as a tumor marker for breast cancer.

Conclusions

Expression of ARMC3 in tumor samples and normal adjacent tissue is very important. The expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. Accordingly, aberrant expression of ARMC3 in tumor samples may be an attractive candidate for use as a tumor marker.

Results

Overall, 43.6% of tumors and 25.6% of normal adjacent tissues expressed ARMC3. ARMC3 was overexpressed in 41% of tumor samples (P = 0.00) and showed decreased expression in 46.2% (P = 0.00). Also, the expression of this gene in 12.8% of tumors was unchanged, which was statistically significant. It should be noted that all samples expressed ACTB gene.

Materials and Methods

Eighty samples including 40 tumor samples and 40 normal adjacent tissue samples, were gathered from the ICBC biobank. RNA extraction was carried out on all samples. The extracted RNA was treated by DNaseI, after which cDNA was synthesized. Expression of ARMC3 with ACTB (internal control) was studied using Real-Time PCR (polymerase chain reaction).

Background

Breast cancer is the most prevalent cancer among women. Biomarkers that are expressed in tumors play a pivotal role in diagnosis and treatment. Cancer-testis (CT) antigens are predominantly expressed in the testis and also have inappropriate expression in various tumor types. In the case of expression in tumors, they will be used as immunotherapy targets.

Objectives

Expression of ARMC3, a CT antigen, was analyzed to determine its potential as a tumor marker for breast cancer.

Breast Cancer;Cancer-Testis Genes;Biomarker Breast Cancer;Cancer-Testis Genes;Biomarker http://www.Biotech-health.portal.tools/index.php?page=article&article_id=34453 Ali-Akbar Zare Ali-Akbar Zare Department of Biotechnology, School of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, IR Iran; Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran Department of Biotechnology, School of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, IR Iran; Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran Keivan Majidzadeh-A Keivan Majidzadeh-A Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran; Tasnim Biotechnology Research Center (TBRC), School of Medicine, AJA University of Medical Sciences, Tehran, IR Iran Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran; Tasnim Biotechnology Research Center (TBRC), School of Medicine, AJA University of Medical Sciences, Tehran, IR Iran Rezvan Esmaeili Rezvan Esmaeili Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran Cancer Genetics Department, Breast Cancer Research Center, ACECR, Tehran, IR Iran Nematollah Gheibi Nematollah Gheibi Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Mohammad Reza Sarookhani Mohammad Reza Sarookhani Department of Biotechnology, Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Biotechnology, Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran. Tel: +98-9121823059, Fax: +98-2833345862 Department of Biotechnology, Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Biotechnology, Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran. Tel: +98-9121823059, Fax: +98-2833345862
en 10.17795/bhs-34608 Reliability and Validity of Short Food Frequency Questionnaire Among Pregnant Females Reliability and Validity of Short Food Frequency Questionnaire Among Pregnant Females research-article research-article Patients and Methods

A total of 553 pregnant females, aged 18 - 40 years, during the third trimester of pregnancy, were included in the study. Statistical analysis of Pearson correlation coefficient, analysis of covariance for logistic regression and factor analysis were performed using SPSS software version 23.

Results

In this study, Pearson correlation coefficients between test and retest for foods was r = 0.845. The Kaiser-Meyer-Oilskin measure of sampling adequacy was 0.584, P values for the Bartlett test of sphericity were all less than 0.001.

Conclusions

The SFFQ has adequate reproducibility and validity for Iranian pregnant females.

Background

The food frequency questionnaire (FFQ) is a standard tool to assess long-term dietary intake. Development, reliability and validity of short FFQ depend on the study objective and population characteristics. However assessment of nutritional status of pregnant females is very important.

Objectives

The current study aimed to examine the reliability and validity of a short food frequency questionnaire among pregnant females in the Qazvin, Iran.

Patients and Methods

A total of 553 pregnant females, aged 18 - 40 years, during the third trimester of pregnancy, were included in the study. Statistical analysis of Pearson correlation coefficient, analysis of covariance for logistic regression and factor analysis were performed using SPSS software version 23.

Results

In this study, Pearson correlation coefficients between test and retest for foods was r = 0.845. The Kaiser-Meyer-Oilskin measure of sampling adequacy was 0.584, P values for the Bartlett test of sphericity were all less than 0.001.

Conclusions

The SFFQ has adequate reproducibility and validity for Iranian pregnant females.

Background

The food frequency questionnaire (FFQ) is a standard tool to assess long-term dietary intake. Development, reliability and validity of short FFQ depend on the study objective and population characteristics. However assessment of nutritional status of pregnant females is very important.

Objectives

The current study aimed to examine the reliability and validity of a short food frequency questionnaire among pregnant females in the Qazvin, Iran.

Diet Surveys;Pregnancy;Validity;Reliability;Food Frequency Questionnaire Diet Surveys;Pregnancy;Validity;Reliability;Food Frequency Questionnaire http://www.Biotech-health.portal.tools/index.php?page=article&article_id=34608 Seyedeh Fatemeh Sharafi Seyedeh Fatemeh Sharafi Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, IR Iran Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, IR Iran Maryam Javadi Maryam Javadi Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, IR Iran; Children Center Growth Research, Qazvin University of Medical Sciences, Qazvin, IR Iran Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, IR Iran; Children Center Growth Research, Qazvin University of Medical Sciences, Qazvin, IR Iran Ameneh Barikani Ameneh Barikani Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Community Medicine, Qazvin University of Medical Sciences, Qazvin, IR Iran Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Department of Community Medicine, Qazvin University of Medical Sciences, Qazvin, IR Iran
en 10.17795/bhs-35914 Kinesin-1 Traffic Control in Neuronal Highway Kinesin-1 Traffic Control in Neuronal Highway review-article review-article Conclusions

In summary, the current review article demonstrated that some proteins such as adaptors, Scaffolds, chaperons and microtubule associated proteins and some metabolites, hormones, protein kinases and exercise training can regulate kinesin-1 traffic control in neuronal highway. These findings open exciting new areas of kinesin-1 research.

Context

The current study aimed to review research articles concerning kinesin-1 traffic control in the neuronal highways

Evidence Acquisition

This review article compromised previous studies published since 1980 using PubMed, Google scholar, Embase, Medline, science direct and SID databases according to the keywords.

Results

Kinesin-1 often recognizes scaffold proteins or adaptor proteins and binds to cargo membrane proteins directly as part of a protein complex. Several kinases and microtubule associated proteins are identified in the regulation of motor-cargo unloading. The mechanisms by which kinesin-1 recognizes and binds to specific cargos, and how to unload cargo and determine the direction of transport, are now identified.

Conclusions

In summary, the current review article demonstrated that some proteins such as adaptors, Scaffolds, chaperons and microtubule associated proteins and some metabolites, hormones, protein kinases and exercise training can regulate kinesin-1 traffic control in neuronal highway. These findings open exciting new areas of kinesin-1 research.

Context

The current study aimed to review research articles concerning kinesin-1 traffic control in the neuronal highways

Evidence Acquisition

This review article compromised previous studies published since 1980 using PubMed, Google scholar, Embase, Medline, science direct and SID databases according to the keywords.

Results

Kinesin-1 often recognizes scaffold proteins or adaptor proteins and binds to cargo membrane proteins directly as part of a protein complex. Several kinases and microtubule associated proteins are identified in the regulation of motor-cargo unloading. The mechanisms by which kinesin-1 recognizes and binds to specific cargos, and how to unload cargo and determine the direction of transport, are now identified.

Kinesin-1;Scaffold Proteins;Adaptor Proteins;Neuronal Transport Kinesin-1;Scaffold Proteins;Adaptor Proteins;Neuronal Transport http://www.Biotech-health.portal.tools/index.php?page=article&article_id=35914 Masoud Rahmati Masoud Rahmati Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, IR Iran; Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, IR Iran. Tel: +98-9124525538, Fax: +98-4215393 Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, IR Iran; Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, IR Iran. Tel: +98-9124525538, Fax: +98-4215393
en 10.17795/bhs-35388 Cytogenetic Evaluation of Couples With Spontaneous Abortion, Still Birth and Recurrent Miscarriage in Qazvin: Report and Review Cytogenetic Evaluation of Couples With Spontaneous Abortion, Still Birth and Recurrent Miscarriage in Qazvin: Report and Review research-article research-article Background

Chromosomal abnormality plays an important role in different types of miscarriages.

Objectives

The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent abortion (RA), spontaneous abortion (SA) and still birth (SB).

Patients and Methods

In this retrospective study, the frequency of chromosomal aberrations was investigated among 260 couples with miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 to 2014. Metaphase spreads were analyzed using G-banding.

Results

In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian translocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples with SA.

Conclusions

In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. Cytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments.

Background

Chromosomal abnormality plays an important role in different types of miscarriages.

Objectives

The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent abortion (RA), spontaneous abortion (SA) and still birth (SB).

Patients and Methods

In this retrospective study, the frequency of chromosomal aberrations was investigated among 260 couples with miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 to 2014. Metaphase spreads were analyzed using G-banding.

Results

In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian translocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples with SA.

Conclusions

In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. Cytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments.

Recurrent Abortion;Spontaneous Abortion;Still Birth, Chromosome Abnormality Recurrent Abortion;Spontaneous Abortion;Still Birth, Chromosome Abnormality http://www.Biotech-health.portal.tools/index.php?page=article&article_id=35388 Reza Najafipour Reza Najafipour Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Javad Ansari Javad Ansari Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Manijeh Jalilvand Manijeh Jalilvand Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Sahar Moghbelinejad Sahar Moghbelinejad Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran. Tel: +98-2813336001, Fax: +98-2813324970 Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran; Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran. Tel: +98-2813336001, Fax: +98-2813324970
en 10.17795/bhs-36029 Happiness Among College Students: A Cross-Sectional Web-Based Study Among Iranian Medical Students Happiness Among College Students: A Cross-Sectional Web-Based Study Among Iranian Medical Students research-article research-article Conclusions

The findings of the present study show that a happiness score among our sample study was slightly low and people with high happiness scores had a healthier lifestyle, i.e. more physical activity and less tobacco smoking. College students should be encouraged to do regular exercise as a way to increase the happiness level.

Results

The mean happiness score was 114.59 ± 18.31. Socio-economic status, physical activity, and experience of stress in the last 6 months were related to the happiness score (P = 0.009, P < 0.001, P < 0.001, respectively). However, gender, cigarette smoking, hookah smoking and body mass index were not significantly correlated with happiness.

Objectives

The aim of the present study was to evaluate happiness among college students of Qazvin University of Medical Sciences in terms of socio-demographic variables.

Materials and Methods

In this cross-sectional web-based study, all the students of Qazvin University of Medical Sciences in Iran who had course classes were invited to participate in the study and 541 students filled out the web-based questionnaire including questions for measuring happiness oxford happiness questionnaire (OHQ), health status, stress experience in the past six months, cigarette and hookah smoking, physical activity rapid assessment of physical activity (RAPA), as well as socio-economic and demographic information.

Background

During the recent decades, happiness and psychological wellbeing have been among the most attractive issues for researchers in the fields of social sciences and health. Medical and paramedical students in comparison with other college students are less happy due to work circumstance in hospital and special education.

Conclusions

The findings of the present study show that a happiness score among our sample study was slightly low and people with high happiness scores had a healthier lifestyle, i.e. more physical activity and less tobacco smoking. College students should be encouraged to do regular exercise as a way to increase the happiness level.

Results

The mean happiness score was 114.59 ± 18.31. Socio-economic status, physical activity, and experience of stress in the last 6 months were related to the happiness score (P = 0.009, P < 0.001, P < 0.001, respectively). However, gender, cigarette smoking, hookah smoking and body mass index were not significantly correlated with happiness.

Objectives

The aim of the present study was to evaluate happiness among college students of Qazvin University of Medical Sciences in terms of socio-demographic variables.

Materials and Methods

In this cross-sectional web-based study, all the students of Qazvin University of Medical Sciences in Iran who had course classes were invited to participate in the study and 541 students filled out the web-based questionnaire including questions for measuring happiness oxford happiness questionnaire (OHQ), health status, stress experience in the past six months, cigarette and hookah smoking, physical activity rapid assessment of physical activity (RAPA), as well as socio-economic and demographic information.

Background

During the recent decades, happiness and psychological wellbeing have been among the most attractive issues for researchers in the fields of social sciences and health. Medical and paramedical students in comparison with other college students are less happy due to work circumstance in hospital and special education.

Happiness;Tobacco Smoking;Life Satisfaction;Physical Activity;Students Happiness;Tobacco Smoking;Life Satisfaction;Physical Activity;Students http://www.Biotech-health.portal.tools/index.php?page=article&article_id=36029 Azadeh Lesani Azadeh Lesani Department of Human Nutrition, Qazvin University of Medical Sciences, Qazvin, IR Iran Department of Human Nutrition, Qazvin University of Medical Sciences, Qazvin, IR Iran Asghar Mohammadpoorasl Asghar Mohammadpoorasl Tabriz Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran; Tabriz Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran Tabriz Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran; Tabriz Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran Maryam Javadi Maryam Javadi Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, IR Iran Hossein Ansari Hossein Ansari Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran Ali Fakhari Ali Fakhari Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, IR Iran Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, IR Iran
en 10.17795/bhs-34642 The Prevalence of Symptomatic Vaginal Candidiasis Among Females in Tehran, 2014 The Prevalence of Symptomatic Vaginal Candidiasis Among Females in Tehran, 2014 brief-report brief-report Background

Vaginitis is the most common gynecological problem and the second most common infection. This condition occurs in approximately 90% of the affected females; secondary to bacterial vaginosis and vulvovaginal candidiasis.

Objectives

According to the high prevalence of vulvovaginal candidiasis in Iran and because of the importance of controlling causing species, the current study aimed to evaluate the prevalence of symptomatic vaginal candidiasis among females referred to the hospitals affiliated to Shahid Beheshti University in Tehran, Iran in 2014.

Patients and Methods

In this cross-sectional study, 580 females suspected of vulvovaginal candidiasis were selected by simple random sampling. In lithotomy position and after using sterile speculum without lubrication a fluid sample was obtained from the upper part of the lateral wall of the vagina and the samples were cultured on agar medium. All samples were examined by the same gynecologist.

Results

The prevalence of vaginal candidiasis was 15.5% and Candida albicans was observed in 92.3% of the subjects.

Conclusions

Candida albicans was the most common cause of vaginal candidiasis.

Background

Vaginitis is the most common gynecological problem and the second most common infection. This condition occurs in approximately 90% of the affected females; secondary to bacterial vaginosis and vulvovaginal candidiasis.

Objectives

According to the high prevalence of vulvovaginal candidiasis in Iran and because of the importance of controlling causing species, the current study aimed to evaluate the prevalence of symptomatic vaginal candidiasis among females referred to the hospitals affiliated to Shahid Beheshti University in Tehran, Iran in 2014.

Patients and Methods

In this cross-sectional study, 580 females suspected of vulvovaginal candidiasis were selected by simple random sampling. In lithotomy position and after using sterile speculum without lubrication a fluid sample was obtained from the upper part of the lateral wall of the vagina and the samples were cultured on agar medium. All samples were examined by the same gynecologist.

Results

The prevalence of vaginal candidiasis was 15.5% and Candida albicans was observed in 92.3% of the subjects.

Conclusions

Candida albicans was the most common cause of vaginal candidiasis.

Prevalence;Vaginal Candidiasis;Candida albicans Prevalence;Vaginal Candidiasis;Candida albicans http://www.Biotech-health.portal.tools/index.php?page=article&article_id=34642 Soheila Nouraei Soheila Nouraei Department of Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Department of Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Farangis Sharifi Farangis Sharifi Department of Midwifery, Kazerun Branch, Islamic Azad University, Kazerun, IR Iran Department of Midwifery, Kazerun Branch, Islamic Azad University, Kazerun, IR Iran Ehsan Shahverdi Ehsan Shahverdi Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran; Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Mollasadra st., Vanaq sq., Tehran, IR Iran. Tel/Fax: +98-2188620826 Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran; Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Mollasadra st., Vanaq sq., Tehran, IR Iran. Tel/Fax: +98-2188620826 Mohammad Amin Konjedi Mohammad Amin Konjedi Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran
en 10.17795/bhs-34433 Experienced and Perceived Stress in Females With Schizophrenia and Healthy Subjects Experienced and Perceived Stress in Females With Schizophrenia and Healthy Subjects research-article research-article Patients and Methods

The study sample included 50 patients with schizophrenia in Tuba rehabilitation center in Ardabil selected by available sampling method. Healthy group participants were selected through cloning by age, gender and marital status of the patient group. The data were collected by the questionnaire of Holmes-Rahe scale and Cohen et al. Data were analyzed by multivariate ANOVA (MANOVA) using SPSS software.

Conclusions

Results showed the levels of perceived stress and negative stress play important role in the creation and maintenance of schizophrenia.

Results

Compared with the normal subjects, patients with schizophrenia had a higher mean score in negative perceived and experienced stresses, but had a lower mean score in positive perceived stress as well as in total perceived stress.

Objectives

The current study aimed to compare perceived stress in females with schizophrenia and that of healthy people.

Background

Schizophrenia is a psychiatric disorder characterized by chronic disturbances of thought and perception.

Patients and Methods

The study sample included 50 patients with schizophrenia in Tuba rehabilitation center in Ardabil selected by available sampling method. Healthy group participants were selected through cloning by age, gender and marital status of the patient group. The data were collected by the questionnaire of Holmes-Rahe scale and Cohen et al. Data were analyzed by multivariate ANOVA (MANOVA) using SPSS software.

Conclusions

Results showed the levels of perceived stress and negative stress play important role in the creation and maintenance of schizophrenia.

Results

Compared with the normal subjects, patients with schizophrenia had a higher mean score in negative perceived and experienced stresses, but had a lower mean score in positive perceived stress as well as in total perceived stress.

Objectives

The current study aimed to compare perceived stress in females with schizophrenia and that of healthy people.

Background

Schizophrenia is a psychiatric disorder characterized by chronic disturbances of thought and perception.

Schizophrenia;Stress;Perceived Stress;Experienced Stress;Females Schizophrenia;Stress;Perceived Stress;Experienced Stress;Females http://www.Biotech-health.portal.tools/index.php?page=article&article_id=34433 Maryam Khodadadi Mogadam Maryam Khodadadi Mogadam Islamic Azad University, Ardabil, IR Iran Islamic Azad University, Ardabil, IR Iran Mehdi Samadzadeh Mehdi Samadzadeh Ardabil University of Medical Sciences, Ardabil, IR Iran; Ardabil University of Medical Sciences, Ardabil, IR Iran Ardabil University of Medical Sciences, Ardabil, IR Iran; Ardabil University of Medical Sciences, Ardabil, IR Iran Bita Shahbazzadegan Bita Shahbazzadegan School of Medicine, Ardabil University of Medical Sciences, Ardabil, IR Iran; Department of Public Health, School of Health, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran School of Medicine, Ardabil University of Medical Sciences, Ardabil, IR Iran; Department of Public Health, School of Health, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Bita Movaffag Bita Movaffag Ardabil University of Medical Sciences, Ardabil, IR Iran Ardabil University of Medical Sciences, Ardabil, IR Iran